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CD34 (Hematopoietic Stem Cell & Endothelial Marker) Antibody - Conjugated to PE
  • 商城价格 登录后可查看价格
  • 货号 LM10331
  • 品牌 Leading Biology ( 经销商 )
  • CAS号 见包装
  • 规格/包装 0.5 ml
  • 单位 个
  • 储存条件 见详情介绍
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品牌：

Leading Biology

货号：

LM10331

规格：

0.5 ml

产品官网链接：

产品分类：

单克隆抗体

研究领域：

产品概述：

This antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi’s sarcoma, but shows low specificity.

来源：

Mouse

靶点/蛋白质：

Blast cells of a chronic myeloid leukemia patient

特异性：

Human, Rat

存储温度：

Store at 2 to 8°C.Antibody is stable for 24 months.

存储溶液：

0.5 ml at 100ug/ml; Conjugated to PE

应用：

参考文献：

1. Felshow DM et al. Blood 97:3768-3775 (2001). 2. Sato T et al. Blood 94:2548-2554 (1999).

详情介绍：

Function Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. Cellular_Location Membrane; Single-pass type I membrane protein Tissue_Location Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues

别名：

Hematopoietic progenitor cell antigen CD34, CD34, CD34

说明书：

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