High Concentration (HC)即高浓度的Matrigel（货号：354248；蛋白浓度18-22 mg/ml）:有利于肿瘤细胞迅速增长、血管生成实验，免疫小鼠注射（肿瘤模型）

Corning® Matrigel® Basement Membrane Matrix High Concentration (HC), *LDEV-Free, 10mL (Product #354248)

Corning Matrigel matrix is a solubilized basement membrane preparation extracted from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma, a tumor rich in extracellular matrix proteins, including Laminin (a major component), Collagen IV, heparin sulfate proteoglycans, entactin/nidogen, and a number of growth factors.

Source
Engelbreth-Holm-Swarm Mouse Tumor

Quality
• Mouse colonies routinely screened for pathogens via Mouse Antibody Production (MAP) testing
• Extensive PCR testing is performed to screen for a number of pathogens
• Tested and found negative for bacteria, fungi, and mycoplasma
• Protein concentrations determined by Lowry method
• Endotoxin units measured by Limulus Amoebocyte Lysate assay
• Matrigel Matrix gel stability is tested for a period of 14 days at 37°C
• Biological activity is determined for each lot using a neurite outgrowth assay.

Preparation and Storage
Store at -20°C. Avoid multiple freeze-thaws.

Application
• Cell Growth and Differentiation
• Metabolism/Toxicology Studies
• Invasion Assays
• In Vitro and In Vivo Angiogenesis Assays
• In Vivo Angiogenesis Studies and Augmentation of Tumors in Immunosuppressed Mice

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