产品名：重组人FGF-21  

产品号：LT-0077

产品信息：

FGF-21是一种分泌生长因子，属于FGF家族成员。这一家族的蛋白通过促进细胞增殖和分化在产前发育、产后生长和各种组织的再生过程中起着中心作用。当β-Klotho作为蛋白共因子存在是，FGF-21通过FGFR 1 c和4受体产生信号,并刺激脂肪细胞进行胰岛素依赖的葡萄糖摄取。重组人FGF-21是一种19.5 kDa蛋白，含有182个氨基酸残基。

别名：Fibroblast Growth Factor-21, FGFL

英文描述：

FGF-21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-21, in the presence of β-Klotho as a protein cofactor, signals through the FGFR 1c and 4 receptors, and stimulates insulin-independent glucose uptake by adipocytes. Recombinant Human FGF-21 is a 19.5 kDa protein containing 182 amino acid residues.

氨基酸序列:

MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS

表达宿主来源:

E.coli

保存条件：

4℃保存6个月，-20℃保存一年或者-80℃长期保存。

纯度&内毒素: 

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level <0.5EU/ug

The purity of rhFGF-21 was determined by SDS-PAGE of non-reduced and reduced rhFGF-21and staining overnight with Coomassie Blue.