产品名：重组人瘦素（Leptin）

产品号：LT-0150

产品信息：

ob(肥胖)基因,编码的瘦素是一种脂肪细胞因子,抑制食欲,增加产热。瘦素已被证明会降低体重,食品消耗,并在各种体内模型中降低血浆葡萄糖水平。重组的人瘦素是一种16.0 kDa蛋白，含有147个氨基酸残基。

别名：Obesity protein (OB)

英文描述：

Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Recombinant Human Leptin is a 16.0 kDa protein containing 147 amino acid residues.

氨基酸序列:

MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL DFIPGLHPIL TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHV LAFSKSCHLP WASGLETLDS LGGVLEASGY STEVVALSRL QGSLQDMLWQ LDLSPGC

表达宿主来源:

E.coli

保存条件：

4℃保存6个月，-20℃保存一年或者-80℃长期保存。

纯度&内毒素: 

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level <0.5EU/ug

The purity of rhLeptin was determined by SDS-PAGE of non-reduced rhLeptin  and staining overnight with Coomassie Blue.