产品名：重组人白介素3（IL-3）

产品号：LT-0113

产品信息：

IL-3是一种造血生长因子。能够促进巨核细胞的祖细胞,颗粒巨噬细胞,红细胞,嗜酸性粒细胞,嗜碱细胞和肥大细胞谱系的维持、分化和增殖。由T细胞,肥大细胞和嗜酸性粒细胞产生,IL-3提高血栓形成,吞噬,抗体介导的细胞毒性。它能激活单核细胞表明IL-3可能有额外的免疫调节作用。许多IL-3活动依赖于与其他细胞因子的共刺激作用。IL-3是一种物种特异性、糖基化的细胞因子。重组的人IL-3 是分子量为15.0 kDa的球状蛋白质，含有133个氨基酸残基。

别名：MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor

英文描述：

IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages.  Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoiesis, phagocytosis, and antibody-mediated cellular cytotoxicity.  Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles.  Many of the IL-3 activities depend upon co-stimulation with other cytokines.  IL-3 is a species-specific, variably glycosylated cytokine.  Recombinant Human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues.

氨基酸序列:

APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF

表达宿主来源:

E.coli

保存条件：

4℃保存6个月，-20℃保存一年或者-80℃长期保存。

纯度&内毒素: 

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level <0.5EU/ug

The purity of rhIL-3 was determined by SDS-PAGE and staining overnight with Coomassie Blue.