产品名：重组人干扰素α2b（IFNα2b）

产品号：LT-0232

产品信息：

干扰素alpha(IFN- alpha)，也叫白细胞干扰素，是一组相关但不同的蛋白质，95%以上的氨基酸序列具有同源性。它们是I型干扰素家族的成员，它们共用一个由两个亚单位组成的普通细胞表面受体，一个100 kDa配体结合亚单元(IFN -alpha R2)和一个125 kDa配体结合和信号转导亚单元(IFN-alpha R1)，它们都参与配体结合和信号转导。IFN - alpha在靶细胞上有抗病毒和免疫调节作用。

别名：

alpha-2a interferon; IFNA; IFNA2; IFNA2b; IFNalpha 2; IFN-alpha 2; IFN-alpha-2; IFN-alphaA; INFA2; interferon alpha 2b; interferon alpha A; interferon alpha-2; Interferon alpha-A; interferon, alpha 2; LeIF A; MGC125764; MGC125765

英文描述：

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

氨基酸序列:

MCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFGFPQEEFGNQFQKAETIPVLHEMIQQIF NLFSTKDSSAAWDETLLDKFYTELYQQLNDLEACVIQGVGVTETPLMKEDSILAVRKYFQRITLY LKEKKYSPCAWEVVRAEIMRSFSLSTNLQESLRSKE

表达宿主来源:

E.coli

保存条件：

4℃保存6个月，-20℃保存一年或者-80℃长期保存。

纯度&内毒素: 

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level <0.5EU/ug

The purity of rhIFNα2b was determined by SDS-PAGE of non-reduced rhIFNα2b  and staining overnight with Coomassie Blue.