产品名：重组人碱性成纤维细胞生长因子( basic FGF, bFGF)

产品号：LT-0068

别名: Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin

产品信息：

basic FGF是FGF家族的23名成员之一。通过促进细胞增殖和分化，这个家族的蛋白在产前发育、产后生长和多种组织再生过程中起着核心作用。basic FGF是一种非糖基化的肝素结合生长因子，表达于大脑、垂体、肾、视网膜、骨、睾丸、肾上腺、肝脏、单核细胞、上皮细胞和内皮细胞。basic FGF通过FGFR 1b、1c、2c、3c和4产生信号。重组人basic FGF是一种17.2 kDa蛋白质，由154个氨基酸残基组成。

适合干细胞使用。

英文描述：

FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues.

氨基酸序列:

AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS

表达宿主来源:

E.coli

保存条件：

4℃保存6个月，-20℃保存一年或者-80℃长期保存

纯度&内毒素:

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level <0.5EU/ug

The purity of rh bFGF  was determined by SDS-PAGE of reduced rh bFGF and staining overnight with Coomassie Blue.