产品名：重组人/小鼠/大鼠BMP2  

产品号：LT-0024

产品信息：

BMPs(骨形成蛋白)属于结构上与信号通道蛋白相关的TGF-β超家族。BMP-2是一种有效的骨诱导细胞因子，与骨诱导载体比如胶原和合成的合成羟磷灰石共同作用可以诱导骨和软骨形成。除了成骨活性外，BMP-2在心脏形态发生中起重要作用，并在各种组织中表达，包括肺、脾、脑、肝、前列腺和小肠。

别名：Bone Morphogenetic Protein-2, BMP-2A

英文描述：

BMPs (Bone Morphogenetic Proteins) belong to the TGF-β superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis, and is expressed in a variety of tissues, including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP-2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond.

氨基酸序列:

MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR

来源:

E.coli

保存条件：

4℃保存6个月，-20℃保存一年或者-80℃长期保存。

纯度&内毒素: 

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level <0.5EU/ug

The purity of rBMP-2 was determined by SDS-PAGE of non-reduced and reduced rBMP-2 and staining overnight with Coomassie Blue.