产品名：重组人G-CSF

产品号：LT0087

产品信息：

G-CSF是一种造血生长因子。能够刺激祖细胞发育成中性粒细胞，增强成熟终末细胞的功能性活动。不同细胞在特定的刺激下会分泌，包括巨噬细胞、成纤维细胞、内皮细胞和骨髓基质。临床上使用G-CSF促进骨髓移植后造血功能恢复。人类和小鼠G-CSF可以交叉反应。重组人G-CSF是一个18.7 kDa蛋白，由174个氨基酸残基组成。

别名：Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSF beta, pluripoietin

英文描述：

G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells, including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant Human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues.

氨基酸序列:

TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPW APLSSCPSQA LQLAGCLSQL HSGLFLYQGL LQALEGISPE LG PTLDTL QLDVADFATT IWQQMEELGM APALQPTQGA MPAFASAFQR RAGG VLVA SHLQSFLEVS YRVLRHLAQP

来源:

E.coli

保存条件：

4℃保存6个月，-20℃保存一年或者-80℃长期保存。

纯度&内毒素: 

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level <0.5EU/ug

The purity of rhG-CSF was determined by SDS-PAGE of non-reduced rhG-CSF and staining overnight with Coomassie Blue.