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产品名：重组人SCF
产品号：LT-0200
产品信息： 造血干细胞因子（stem cell factor，SCF）与IL-3、GM-SCF、EPO、IL-4、IL-6、IL-9等有较强的协同作用，对粒系、淋巴系、红系和巨噬细胞系均有刺激生长作用。 别名:Stem Cell Factor, c-Kit Ligand, Mast Cell Growth Factor (MGF), Steel Factor
英文描述: SCF is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. The human SCF gene encodes for a 273 amino acid transmembrane protein, which contains a 25 amino acid N-terminal signal sequence, a 189 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 36 amino acid cytoplasmic domain. The secreted soluble form of SCF is generated by proteolytic processing of the membrane anchored precursor. Recombinant Human SCF is an 18.4 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.
氨基酸序列: MEGICRNRVTNNVKDVTKLVANLPKDYMITLKYVPGMDVLPSHCWISEMVVQLSDSLTDLLDKFSNISEGLSNYSIIDKLVNIVDDLVECVKENSSKDLKKSFKSPEPRLFTPEEFFRIFNRSIDAFKDFVVASETSDCVVSSTLSPEKDSRVSVTKPFMLPPVA
来源:E.coli
保存条件：4℃保存6个月，-20℃保存一年或-80℃长期保存。
纯度&内毒素： Greater than 95% by SDS-PAGE gel and HPLC analyses. Endotoxin Level<0.5EU/μg
The purity of rhSCF was determined by SDS-PAGE of reduced rhSCF and staining overnight with Coomassie Blue.
温馨提示：该产品提供免费试用装，欢迎咨询。QQ：2630530262
产品号：LT-0200
产品信息： 造血干细胞因子（stem cell factor，SCF）与IL-3、GM-SCF、EPO、IL-4、IL-6、IL-9等有较强的协同作用，对粒系、淋巴系、红系和巨噬细胞系均有刺激生长作用。 别名:Stem Cell Factor, c-Kit Ligand, Mast Cell Growth Factor (MGF), Steel Factor
英文描述: SCF is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. The human SCF gene encodes for a 273 amino acid transmembrane protein, which contains a 25 amino acid N-terminal signal sequence, a 189 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 36 amino acid cytoplasmic domain. The secreted soluble form of SCF is generated by proteolytic processing of the membrane anchored precursor. Recombinant Human SCF is an 18.4 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.
氨基酸序列: MEGICRNRVTNNVKDVTKLVANLPKDYMITLKYVPGMDVLPSHCWISEMVVQLSDSLTDLLDKFSNISEGLSNYSIIDKLVNIVDDLVECVKENSSKDLKKSFKSPEPRLFTPEEFFRIFNRSIDAFKDFVVASETSDCVVSSTLSPEKDSRVSVTKPFMLPPVA
来源:E.coli
保存条件：4℃保存6个月，-20℃保存一年或-80℃长期保存。
纯度&内毒素： Greater than 95% by SDS-PAGE gel and HPLC analyses. Endotoxin Level<0.5EU/μg
The purity of rhSCF was determined by SDS-PAGE of reduced rhSCF and staining overnight with Coomassie Blue.
生物活性：
The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 1.718ng/mL, corresponding to a specific activity of ≥ 5.8×10^5 U/mg.
温馨提示：该产品提供免费试用装，欢迎咨询。QQ：2630530262