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重组人白细胞介素6(IL-6)
  • 商城价格 登录后可查看价格
  • 货号 LT-0116-01M
  • 品牌 志道生物 ( 生产厂家 )
  • CAS号
  • 规格/包装 1mg
  • 单位 北京志道生物科技有限公司
  • 储存条件
  • 现货状态 三个工作日

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产品名:重组人白介素6 (IL-6)/ Recombinant Human IL-6

产品号:LT0116 产品信息: 白细胞介素-6,简称白介素6 (IL-6),是一种细胞因子,属于白细胞介素的一种。它是由纤维母细胞、单核/巨噬细胞、T淋巴细胞、B淋巴细胞、上皮细胞、角质细胞、以及多种瘤细胞所产生。IL-1、TNF-α, PDGF、病毒感染、双链RNA及c AMP等,均可诱导正常细胞产生白介素6。白介素6能够刺激参与免疫反应的细胞增殖、分化并提高其功能。

别名: IFN-β2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2

英文描述: IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant Human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.

表达宿主来源: E.coli

氨基酸序列: PVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM

保存条件: 4℃保存6个月,-20℃保存一年或-80℃长期保存。

纯度&内毒素 Greater than 95% by SDS-PAGE gel and HPLC analyses. Endotoxin Level<0.5EU//μg The purity of rhIL6 was determined by SDS-PAGE of reduced rhIL6 and staining overnight with Coomassie Blue.

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