SKF 96365 hydrochloride is a synthetic blocker of CaV3 (T-type) voltage gated calcium channels and of TRPC channels. In addition, it has a blocking effect on potassium channels. SKF also inhibits the calcium sensor STIM1 which enables Store-operated Ca2+ entry (SOCE). SKF has an effective concentration of 1-100 µM and an IC50 of 560 nM for CaV3.1 channel. SKF is used to identify CaV3 and TRPC channels in many cell types.
郑重提醒：艾美捷科技最专业的离子通道研究工具供应商Alomone的中国区代理，我们为您提供的如下生命科学领域研究方案享誉海内外：离子通道研究领域、G蛋白耦联受体研究领域、 神经信号通路研究。我们也将一如既往更加努力为国内用户提供快捷、方便的高质量产品，同时更为您售前售后全面技术支持。欢迎垂询：400-6800-868，www.amyjet.com