Imperatoxin A (IpTxa) is a 33 amino acid natural peptidyl toxin isolated from the venom of scorpion Pandinus imperator. IpTxa interacts specifically and activates the Sarcoplasmic reticulum Ca2+-release channel of skeletal and cardiac muscle (ryanodine receptor 1 and 2). It reversibly enhances binding of ryanodine to the receptors. The activating effect of IpTxa on skeletal ryanodine receptor is Ca2+-dependent, synergized by caffeine, and independent of other modulators of RyRs.
郑重提醒：艾美捷科技最专业的离子通道研究工具供应商Alomone的中国区代理，我们为您提供的如下生命科学领域研究方案享誉海内外：离子通道研究领域、G蛋白耦联受体研究领域、 神经信号通路研究。我们也将一如既往更加努力为国内用户提供快捷、方便的高质量产品，同时更为您售前售后全面技术支持。欢迎垂询：400-6800-868，www.amyjet.com