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This non-NMDA receptor antagonist inhibits [3H]AMPA binding to quisqualate receptors at submicromolar concentrations. CNQX also selectively blocks the excitatory action of quisqualate and kainate on spinal neurons with little or no effect on that of NMDA.
The concentrations that inhibit 50% of [3H]AMPA binding (IC50) for CNQX in dorsal horn neurons is 300 nM.郑重提醒:艾美捷科技最专业的离子通道研究工具供应商Alomone的中国区代理,我们为您提供的如下生命科学领域研究方案享誉海内外:离子通道研究领域、G蛋白耦联受体研究领域、 神经信号通路研究。我们也将一如既往更加努力为国内用户提供快捷、方便的高质量产品,同时更为您售前售后全面技术支持。欢迎垂询:400-6800-868,www.amyjet.com