This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.
Research Field
Cardiovascular
Product Categories
Primary antibody
Host
Rabbit
Reactivity
Human,Mouse,Rat
Application
WB,IHC-F,IHC-P,ICC/IF
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Molecular Weight
Calculated MW: 53kDa
Clonality
Polyclonal Antibody
Clonality No.
-
Isotype
IgG
Immunogen
KLH conjugated synthetic peptide derived from human CYP11A1/P450SCC
Purification
affinity purified by Protein A
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Buffer System
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
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